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You are here: Home / Awards / 2025 Category Awards

2025 Category Awards

**In accordance with updated guidelines from our university’s youth programs office, we will no longer display the name, school or district information of TXSEF finalists on our website. This change aims to limit the amount of identifiable information available online, thereby enhancing the protection of student finalists’ identities and personal information. Thank you for your understanding and cooperation.

Animal Sciences

Senior Division

  • First Place: Utilizing Ants to Mitigate MSW Landfill-Derived Methane Production through Novel Aerobic Digester System for Anthropogenic Food Waste Decomposition
  • Second Place: Leptin Neutralizing Antibodies: A Novel and Safe Approach to Obesity Treatment, Liver Fibrosis Reversal, and Metabolic Disorder Mitigation in Mus musculus
  • Third Place: Honeyball

Junior Division

  • First Place: Classifying species of North Texas mosquitoes using computer vision
  • Second Place: The Effect of Sunscreen on Daphnia’s Heart Rate
  • Third Place: Heartbeat of a Horse

Behavioral and Social Sciences

Senior Division

  • First Place: Enhancing Autism Therapeutics: The Influence of Acute Cannabidiol Treatment and the Estrous Cycle on Social Behavior and Hormone Changes in Adult Male and Female Mice

  • Second Place: AutiScan: Development of a Predictive Computational Model for Assessing Probabilities of Neurobehavioral Symptoms of Autism Spectrum Disorders Based on MRI-Derived Structural Metrics, with a Focus on Cerebellum Volume and Phenotypic Correlations in ASD

  • Third Place: Implementation of the AM141 strain C. elegans model of Huntington’s Disease to introduce antioxidants and disaccharides in order to analyze the preventability and reduction of glutamine-40 accumulation through the observation of mobility and essential life processes.

Junior Division

  • First Place: MINDFUL: Measuring Individual Neurodiversity with Dimensionality and Five-factor Understanding of Labels

  • Second Place: Detection and Analysis of Hand Tremors Using Gyroscopic and Accelerometric Data for Early Parkinson’s Disease Indication
  • Third Place: Anonymity, A Missing Family Tree, A Study of People Facing This Reality

Biochemistry

Senior Division

  • First Place: One Blood Drop to New Hope: A Novel Test Method to Improve Fertility Assessment

  • Second Place: Medicine in the Nanosphere: Evaluating the Toxicity of Red Gold, Blue Gold, and Silver Nanoparticles with and without the addition of Sodium Thiosulfate on Daphnia magna and Baker Yeast, with the Development of a Transdermal Microneedle Patch for Nanoparticle Administration

  • Third Place: Targeting Cellular Senescence: In Silico Chemoinformatics Screening of Bioactive Compounds for Inducing Senolysis to Advance Geriatric Therapies

Junior Division

  • First Place: Reducing Risk of Cancer Through Antioxidants

  • Second Place: Living Lightbulbs

  • Third Place: Finding the Best Skin Moisturizer Without Propylene Glycol

Biomedical and Health Sciences

Senior Division

  • First Place: Paving the Path to the Impossible: Regenerating Neurons using Prostaglandin E2 regulation as a therapeutic strategy

  • Second Place: Optimizing Liver Transplant Success: A Data-Driven Approach Incorporating MELD for Accurate Survival Prediction and Equitable Organ Allocation

  • Third Place: Targeting pMHC: A Novel Tripartite In-Silico Approach for Liposome-Aided Ultralong Antibody Therapy in Colorectal Cancer Variants

Junior Division

  • First Place: Enhancing Breast Cancer Image Analysis with a Customized High Accuracy Machine Learning Model

  • Second Place: Guardians of the Flare: Biomedical Insights into UV Protection and Skin Cancer Prevention

  • Third Place: TERTing the Tide: Repurposing FDA-Approved Therapeutics for Cancer Treatment

Biomedical Engineering

Senior Division

  • First Place: NeuroFlex: A Cost-Effective, Non-Invasive EEG-Controlled Bionic Prosthesis for Transfemoral Amputees

  • Second Place: A Novel Stem Cell Bioreactor Design Utilizing Mechanical Stretching and Extracellular Matrix Mimicry

  • Third Place: Wearable, High Sensitivity Bio-Transistor for the Detection of Lactate in Sweat (Year II)

Junior Division

  • First Place: Development of a home-based, stage-specific diagnostic kit for the detection of protein biomarkers to enhance diagnostic capabilities and improve treatment precision for Cancer

  • Second Place: Investigating Genetic Mutations In Glioblastoma Multiforme: Understanding Tumor Progression And Identifying Targets For Effective Therapies

  • Third Place: VNS Seizure Prevention Tech (Vagus Nerve Stimulation)

Cellular and Molecular Biology

Senior Division

  • First Place: Assembling Multifunctional Drug Capsules from Safe and Accessible Materials for Selective Cancer Treatment and Diagnosis: Synergizing Fluorescent and Iron-Based Magnetic Therapy.

  • Second Place: Magnesium Transporter Protein 1 Is An Obligatory Component Of Endoplasmic Reticulum Mg2+ Uptake: A Computational and In Vitro Analysis of Its Role in Divalent Mg2+ cation Homeostasis

  • Third Place: Mitochondrial Chaperones, A Novel Therapeutic Target in Cancer Therapy: Utilization of mtHsp70/GRP75 Inhibition to Enhance Anti-tumor Effects of Chemotherapy in Neuroblastoma

Junior Division

  • First Place: Healing Eczema: Unveiling the Cellular Power of Natural Ingredients

  • Second Place: Using Inducer (IPTG) to Boost L-Asparaginase Production for Anti-Tumor Treatment and Acrylamide Mitigation

  • Third Place: Cellular Contrasts: The Impact of Smoking on Our Body’s Building Blocks

Chemistry

Senior Division

  • First Place: Translation Between the Opacity of Photochromic Dye and UV Index

  • Second Place: Cyclometalated Platinum Complexes for Phosphorescent Organic Light-Emitting Diodes

  • Third Place: Devising Metal-Organic Framework Technology for Scalable Direct Air Capture of CO₂

Junior Division

  • First Place: Computational Simulations of Antibody Binding to VAPB Receptors for Targeted Therapy in Medulloblastoma

  • Second Place: From Trash to Treasure: Exploring Pectin Extraction from Watermelon Rindst

  • Third Place: Polarization is Not Vexation: The Effect of Chiral Solutions on Polarized Light

Computational Biology and Bioinformatics

Senior Division

  • First Place: HMM & Structural Docking In Silico Framework for Identifying & Inhibiting CCN3 Protein Pathway Mutations for Osteosarcoma

  • Second Place: Modulating Tau Pathology: Identifying a Novel Inhibitor for the Suv39h1 Protein Using a Multi-Omic, Attention-Based Neural Network Approach to Treat Alzheimer’s Disease

  • Third Place: SARCOMA-Net:Personalized Sarcoma Therapies through Spatial-Transcriptomic Biomarker Analysis and Variational Autoencoder Drug Generation

Junior Division

  • First Place: Tandem Repeat Analysis and Visualization Atlas (TRAVA)

  • Second Place: Computational Simulations of RNA-Based Aptamers Targeting Epidermal Growth Factor Receptor (EGFR)+ Cells in Glioblastoma

  • Third Place: AI-Mediated Computational Modeling of FK506-Binding Protein 12 (FKBP12)-Enhanced CAR T-Cell Therapy for Targeted Glioblastoma Treatment

Earth and Environmental Sciences

Senior Division

  • First Place: Acoustic Filtration II: Scaling an Ultrasonic Microplastic Filtration Device and Exploring the Physical Phenomenon of Acoustic Blocking

  • Second Place: Cost-Effective, Mobile Rover-AI System Engineered to Evaluate Impacts of Microclimatic Interactions on Pediatric Asthma

  • Third Place: A Novel Evaluation of Natural Sunscreen Compounds as Eco-Sustainable Alternatives to Reduce Anthropogenic Impacts on Aquatic Systems

Junior Division

  • First Place: The Ground Truth: A Novel Approach for Landslide Prediction with a Deep Learning Framework

  • Second Place: Bio-Concrete: Using Living Bacteria to Create Self-Healing Concrete and perform Carbon sequestration

  • Third Place: The Use of Natural Materials to Remove Microplastics from Water

Embedded Systems

Senior Division

  • First Place: Giving Robot Hands a Feeling

  • Second Place: SubArc: An Inexpensive, High Resolution, Open Source, Absolute Magnetic Rotary Encoder
  • Third Place: ImpairiLink: a novel and revolutionary attentiveness aid system utilizing haptics and machine learning for the visually impaired.

Junior Division

  • First Place: Foundation Tilt Prevention System: Protecting Structural Integrity Against Moisture Fluctuations While Optimizing Water Usage

  • Second Place: Beyond the punch: Conceptualizing the StrikeSense into karate sparring

  • Third Place: A Novel AI Approach for Detection of Microplastics

Energy: Sustainable Materials & Design

Senior Division

  • First Place: Enhancing Efficiency in Quantum Dot Solar Cells through Quantum Computational Simulations for Sustainable Energy and Environmental Health

  • Second Place: Testing Parts of a Thermoelectric Generation Device to Optimize Voltage and Current Output by using Temperature Gradients

  • Third Place: “The Bionic Leaf”: Developing a Novel Self-Healing, Bi-Functional Nickel Oxide Catalyst to Use with the Bacterium Ralstonia eutropha for Sustainable Ethanol Production

Junior Division

  • First Place: Micro’fat’ories: Increasing microalgal biomass and lipids for biofuel production

  • Second Place: The Impact of Water Type, Alkalinity, and Current Input on Green Hydrogen Production Efficiency in Water Electrolysis

  • Third Place: Factors Affecting Fuel Cell Energy Efficiency

Engineering Technology: Statics and Dynamics

Senior Division

  • First Place: HandTalk: A Two-Way Translation System for American Sign Language

  • Second Place: Automated Surgical System Integrating an Intelligent Soft Robotics Surface and a Smart Robotic Arm

  • Third Place: SmartPanel: An ML-Assisted Active Control System for Reducing Solar Array Vibrations of Satellites

Junior Division

  • First Place: Flying High

  • Second Place: Solar Tracking Panel

  • Third Place: How nozzle geometries effect propulsion efficiencies.

Environmental Engineering

Senior Division

  • First Place: CyanoHUB: A Data-Driven Harmful Algal Bloom Prediction & Control System Utilizing Nanobubble Technology

  • Second Place: Catalyzing Plastic Degradation: A Novel Mechanochemistry Treatment for Sustainable Plastic Waste Management

  • Third Place: Developing an ecofriendly, cost effective, commercial grade Bio-SIP(Biological Grade structural insulated panel ) for hurricane proof home

Junior Division

  • First Place: Sticking to a Greener World: Finding a Suitable Replacement for Plastic Lollipop Sticks

  • Second Place: Building a Carbon-Free Future: Exploring Optimal Conditions For Carbon Capture

  • Third Place: The MNP Smart Bin

Materials Science

Senior Division

  • First Place: Anticorrosive Strategies for Cu-Al Wire-Bonded Devices in Extreme Automotive Applications

  • Second Place: PLA-Chitosan Composites as Sustainable Alternatives for Menstrual Pads

  • Third Place: Quantum Dots-modulated Associative Learning and Artificial Intelligence

Junior Division

  • First Place: Development and Characterization of Hydrogel Systems for Encapsulation and Controlled Release of Model Compounds

  • Second Place: Eco-Starch: Innovative Solutions for Oil Spill Cleanup

  • Third Place: Creating Environmentally Friendly Biodegradable Plastics Using Potato Peels

Mathematics

Senior Division

  • First Place: A Novel Optimizer Equation to Predict KI67 Scores from Breast Cancer WSIs with CNN

  • Second Place: Utilizing Wavelet Transform and Fourier Transform to Detect Cardiac Arrest Through Electrocardiogram Analysis

  • Third Place: Quantum-Resilient Polynomial Matrix and Modular Transformations for Cryptographic Resilience

Junior Division

  • First Place: Beyond the Curve: A Novel Mathematical Formula for Measuring Volume Under a 3D Parabolic Arch for Sustainable Agricultural Water Consumption.

  • Second Place: Q-safe: Mitigating Quantum Threats with Lattice-Based Cryptography

  • Third Place: Detecting breast cancers using machine learning approaches

Microbiology

Senior Division

  • First Place: Paracoccus for Bioremediation: Optimizing Formate Dehydrogenase in Paracoccus denitrificans for Development of a Non-toxic Bioremediation Strategy for Toxic C1 Compounds in Water

  • Second Place: Unraveling Infant Allergy Risk: Solid Food Introduction Timing, Selection, and Gut Microbiome Axis

  • Third Place: Investigating the Correlation between the Concentration of Calcium Chloride involved in Gene Insertion and its Effect on Transformation Efficiency

Junior Division

  • First Place: The Effects of Glyphosate on Microbial Health
  • Second Place: Effects of Different Natural Antibiotics on Bacteria Inhibition
  • Third Place: Comparing the Effectiveness of a Prescription Antibiotic with Natural Antibiotics and Using Cocktail Therapy to Eradicate Escherichia coli

Physics and Astronomy

Senior Division

  • First Place: The Power of a Star in a Jar: Using Nuclear Fusion for Medical Radioisotope Production.

  • Second Place: OptiSkew: A Biophysical Approach for Self Diagnosis Eye Refractive Disorders

  • Third Place: Searching for the Missing Mass: A Novel Utilization of Artificial Intelligence for Gravitational Microlensing Detection and Dark Matter Discoveries

Junior Division

  • First Place: T CrB: Visualizing the Potential of Exoplanet Transit Data in Predicting Nova Event

  • Second Place: The Sounds of Science: Water Cymatic Vibrations

  • Third Place: AIM-BASE: AI integrated model to predict the Energy consumption of Extraterrestrial Colonies

Plant Sciences

Senior Division

  • First Place: A Green Alliance: Evaluating the Synergistic Dynamics of PETase Expression and Plant-Microbe Interactions in Enhancing Microplastic Degradation Pathways in S. alterniflora

  • Second Place: Examining the Synergistic Effects of Hydrotropism, Magnetotropism, and Simulated Microgravity on Allium fistulosum Morphology Using a Novel 3D Clinostat

  • Third Place: Impact of Tire-Wear Microplastics and Associated Metal Toxicity on the Efficacy of Aerobic Respiration and Proliferation of Algae

Junior Division

  • First Place: Impact of Phaseolus Vulgaris (Red Silk Bean) Seed Priming on Drought Tolerance

  • Second Place: Which Farming Method has more Phytochemical content: Organic or Conventionally Grown?

  • Third Place: Exploring Hydrogels for Sustainable Agriculture

Robotics and Intelligent Machines

Senior Division

  • First Place: AutoMates: Automating With Self-Learning Intelligent Agents

  • Second Place: Soft Robotics in Gastrointestinal Endoscopy: Engineering a Novel Hydraulic Colonoscope to Minimize Risks and Enhance Usability

  • Third Place: NeuroSim – A Digital Twin-Enhanced Sim-to-Real Autonomous Neurosurgical Robot Using Deep Learning

Junior Division

  • First Place: Smartphone-Integrated Retinal Imaging and Skin Analysis System Utilizing Neural Networks

  • Second Place: Autonomous Car Electrical (A.C.E)

  • Third Place: A novel approach to identifying Mosquito Breeding Grounds with Convolutional Neural Networks, to stop the spread of Vector-Borne Diseases.

Systems Software

Senior Division

  • First Place: AssemblyComplete: 3D Combinatorial Construction with Deep Reinforcement Learning

  • Second Place: Implementation and Evaluation of Quantum Key Distribution in Secure Messaging Systems

  • Third Place: Unobstructing voice for the deaf: A real-time centered sign language recognition system

Junior Division

  • First Place: The Blockchain Exploit Playground: Learning Real-World Blockchain Vulnerabilities through an Open-Source Educational Platform for a Secure Future

  • Second Place: Face Recognition And Identification Algorithm For School Attendance

  • Third Place: Nail Disease Detection using CNN

Translational Medical Sciences

Senior Division

  • First Place: Neuroprotective Effects of Nutraceutical Supplementation for Chronic Traumatic Encephalopathy

  • Second Place: A Novel Multi-Target Drug with Nanoparticle Precision for Triple-Negative Breast Cancer : Inhibitron-LC

  • Third Place: An Inverse QSAR Approach to Designing MDM2 Inhibitors For Targeted Therapy of Soft-Tissue Cancers

Junior Division

  • First Place: Nanocurc Gel for Smart Wound Biosensing and Healing

  • Second Place: PROPHYLACTIC MOISTURIZING: A COST-EFFECTIVE THERAPEUTIC TREATMENT OF USING NATURAL OILS AS A TOPICAL EMOLLIENT FOR ATOPIC DERMATITIS TO RETAIN WATER CONTENT IN STRATUM CORNEUM

  • Third Place: Can We Predict Immunotherapy Outcomes in Cancer Patients? Exploring Gene Signatures

 

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